DSPE-PEG2000-COOH
DSPE-PEG2000-COOH•LNP
Structure: 
产品编号
CH51054
CAS
474922-20-8
分子式
(C2H4O)nC46H88NO13P
分子量
2000 (Average)
规格标准
| Catalog No. | CH51054 |
| CAS No. | 474922-20-8 |
| Molecular Formula | (C2H4O)nC46H88NO13P |
| Molecular Weight | 2000 (Average) |
品类工艺支持
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
概况
DSPE-PEG2000-COOH (CAS 474922-20-8, MF (C2H4O)nC46H88NO13P, MW 2000 (Average)) is a PEG-lipid conjugate used as a stealth or functional component in nucleic-acid delivery systems. Practical chemistry questions involve PEG repeat distribution, lipid anchor integrity, and terminal-group functionalisation strategy. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
应用
- DSPE-PEG2000-COOH (CAS 474922-20-8) preparation, route refinement, and analytical-control planning
- PEG length and lipid-anchor variation studies for nucleic-acid delivery
- Custom synthesis of PEG-lipid analogs with controlled molecular weight
- Analytical method development for PEG-lipid characterisation