
1-Palmitoyl-sn-glycero-3-phosphoethanolamine
化学名称
[(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] hexadecanoate
1-Palmitoyl-sn-glycero-3-phosphoethanolamine•LNP
Structure: 

产品编号
CH51055
CAS
53862-35-4
分子式
C21H44NO7P
分子量
453.55
规格标准
| Catalog No. | CH51055 |
| CAS No. | 53862-35-4 |
| Molecular Formula | C21H44NO7P |
| Molecular Weight | 453.55 |
品类工艺支持
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
概况
1-Palmitoyl-sn-glycero-3-phosphoethanolamine (also known as [(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] hexadecanoate) (CAS 53862-35-4, MF C21H44NO7P, MW 453.55) belongs to the helper phospholipid class used in nucleic acid delivery system research and liposomal drug carriers. Typical chemistry topics include stereo-purity at the glycerol backbone, residual free fatty acid, and related diacyl regio-isomers. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
应用
- 1-Palmitoyl-sn-glycero-3-phosphoethanolamine (CAS 53862-35-4) route review and custom analog preparation
- Helper phospholipid component in LNP and liposomal formulation research
- Bilayer-property studies in nucleic-acid delivery system development
- Pulmonary surfactant and biophysical research applications