Oligonucleotide Synthesis, RNA Raw Materials & Modification

2'-Deoxyadenosine Monohydrate

(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol;hydrate

产品编号CH64001CAS号16373-93-6纯度100%

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产品概述

快速信息

产品系列: Oligonucleotide Synthesis, RNA Raw Materials & Modification
化学名称: (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol;hydrate
分子式: C10H15N5O4
分子量: 269.26
纯度: 100%

2'-Deoxyadenosine monohydrate is the hydrated dAdo form of the purine DNA nucleoside, with adenine linked to 2-deoxy-β-D-ribose. CH64001 is identified by CAS 16373-93-6, molecular formula C10H15N5O4, molecular weight 269.26, and PubChem CID 9549172.

Keep this record separate from anhydrous 2'-deoxyadenosine, which is listed separately as CH64007. In research literature, 2'-deoxyadenosine appears as a deoxynucleoside-kinase substrate and as the natural dA reference in polymerase and nucleoside-chemistry studies.

同义词

2'-Deoxyadenosine monohydrate; dAdo monohydrate; 2'-deoxyriboadenosine hydrate

身份与规格

Catalog No.	CH64001
CAS No.	16373-93-6
Molecular Formula	C10H15N5O4 (monohydrate)
Molecular Weight	269.26 (monohydrate)
PubChem CID	9549172
InChIKey	WZJWHIMNXWKNTO-VWZUFWLJSA-N
Purity	100%

储存条件

2-8 C

技术属性

Nucleobase: Adenine
Sugar: 2'-Deoxyribose
Nucleoside class: Purine 2'-deoxyribonucleoside
Material form: Monohydrate
Packaging: Custom packaging on request
Water content: 5-7.5%
Physical form: White to almost white crystal to powder

应用背景

Kinase phosphorylation research: literature reports 2'-deoxyadenosine as a substrate for deoxycytidine kinase and adenosine kinase.
Polymerase building-block studies: modified dA building blocks are compared against the natural deoxyribonucleoside scaffold during polymerase-incorporation research.
Nucleoside chemistry reference: the hydrated dAdo record provides a defined 2'-deoxyribonucleoside identity for DNA and oligonucleotide chemistry work.

公开来源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem 化合物 9549172
PubChem · CID 9549172

常见问题

Is CH64001 the monohydrate or anhydrous form?

It is the monohydrate (CAS 16373-93-6, C10H15N5O4, MW 269.26). The anhydrous 2'-deoxyadenosine (CAS 958-09-8) is listed as a separate CHEMOS product.

How is 2'-deoxyadenosine used as a kinase substrate?

It is phosphorylated by deoxycytidine kinase and adenosine kinase, so it is used as a defined purine deoxynucleoside substrate in kinase phosphorylation research.