Ac4ManNAz
[(2R,3S,4R,5S)-3,4,6-triacetyloxy-5-[(2-azidoacetyl)amino]oxan-2-yl]methyl acetate
产品概述
快速信息
- 产品系列
- Click Chemistry & Bioconjugation Reagents
- 化学名称
- [(2R,3S,4R,5S)-3,4,6-triacetyloxy-5-[(2-azidoacetyl)amino]oxan-2-yl]methyl acetate
- 分子式
- C16H22N4O10
- 分子量
- 430.37
- 纯度
- 99.80000% (HPLC)
Ac4ManNAz is a tetraacetylated N-azidoacetylmannosamine derivative used as a ManNAz metabolic glycan reporter in research workflows involving azido-modified sialic-acid glycans. PubChem records it as CID 71311757, CAS 361154-30-5, molecular formula C16H22N4O10, molecular weight 430.37, exact mass 430.13359291, and InChIKey HGMISDAXLUIXKM-LIADDWGISA-N.
The acetylated ManNAz scaffold supports metabolic glycan-engineering studies, while the azide handle enables downstream bioorthogonal tagging with suitable alkyne probes in analytical glycan-labeling workflows.
同义词
Ac4ManNAz; 1,3,4,6-tetra-O-acetyl-N-azidoacetylmannosamine; tetraacetylated N-azidoacetylmannosamine; ManNAz tetraacetate
身份与规格
| Catalog No. | CH70476 |
| Product Name | Ac4ManNAz |
| CAS No. | 361154-30-5 |
| Molecular Formula | C16H22N4O10 |
| Molecular Weight | 430.37 |
| Exact Mass | 430.13359291 |
| PubChem CID | 71311757 |
| InChIKey | HGMISDAXLUIXKM-LIADDWGISA-N |
| Synonyms | 1,3,4,6-tetra-O-acetyl-N-azidoacetylmannosamine; ManNAz tetraacetate |
| Purity | 99.80000% (HPLC) |
储存条件
-20 C
技术属性
- Sugar scaffold
- N-acetylmannosamine analog
- Sugar protection
- Tetra-O-acetyl
- Chemical-reporter handle
- N-azidoacetyl group
- Labeling role
- Metabolic glycan reporter precursor
- Packaging
- 5 mg; 100 mg; 5 x 5 mg; Custom packaging on request
- Physical form
- Solid
- Stability
- >=4 years
应用背景
- Metabolic glycan-engineering research: Ac4ManNAz is a ManNAz tetraacetate reporter used in studies involving azido-modified sialic-acid glycans.
- Bioorthogonal tagging workflows: the azide handle supports downstream ligation with compatible alkyne probes for detection, enrichment, or imaging workflows in research settings.
- Analytical glycomics context: Ac4ManNAz is relevant to workflows that label sialylated glycans before downstream analysis of glycoconjugates or sialoglycoproteins.
补充物料信息
用途
Use in research workflows that require a ManNAz-derived azido sugar reporter for studying azido-modified sialic-acid glycans and related glycoconjugates. Keep interpretation tied to the experimental system and analytical controls.
特性
Ac4ManNAz combines a protected ManNAz sugar scaffold with an azidoacetyl reporter handle. The tetraacetylated form is used in metabolic glycan-engineering workflows, and the azide supports downstream bioorthogonal tagging with compatible alkyne probes.
相关技术资源
公开来源
- A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems
Journal of the American Chemical Society, 2004
Product-family technical context
- Copper-free click chemistry for dynamic in vivo imaging
Proceedings of the National Academy of Sciences, 2007
Product-family technical context
- A Strain-Promoted [3 + 2] Azide–Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems
Journal of the American Chemical Society, 2004
Product-family technical context
- Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels–Alder Reactivity
Journal of the American Chemical Society, 2008
Product-family technical context
- PubChem 化合物 71311757
PubChem · CID 71311757
常见问题
What is Ac4ManNAz?
Ac4ManNAz is a tetraacetylated N-azidoacetylmannosamine derivative, also described as ManNAz tetraacetate. PubChem records it as CID 71311757 with CAS 361154-30-5.
How is Ac4ManNAz used in research workflows?
It is used as a ManNAz metabolic glycan reporter in research workflows involving azido-modified sialic-acid glycans. The azide handle can be paired with compatible alkyne probes for downstream bioorthogonal tagging.
Is Ac4ManNAz the same as Ac4GlcNAz?
No. Ac4ManNAz and Ac4GlcNAz share the same molecular formula but differ by sugar stereochemistry and PubChem identity. Ac4ManNAz is the ManNAz tetraacetate reporter for sialic-acid glycan workflows.
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