NH2 DOTA-GA
化学名称
5-(2-aminoethylamino)-5-oxo-2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]pentanoic acid
NH2 DOTA-GA•DOTA
Structure: 
产品编号
CH54008
CAS
1639843-65-4
分子式
C21H38N6O9
分子量
518.57
规格标准
| Catalog No. | CH54008 |
| CAS No. | 1639843-65-4 |
| Molecular Formula | C21H38N6O9 |
| Molecular Weight | 518.57 |
品类工艺支持
CHEMOS supports DOTA chelator and radiopharmaceutical building-block chemistry, including protected, activated, PEG-spaced, and conjugation-ready intermediates. DOTA and DOTA-GA derivatives : protected chelators, activated esters, maleimide derivatives, and linker-spaced variants. Custom chelator-linker synthesis : route design for chelator-linker-targeting moiety intermediates. Metal-sensitive process control : purification and analytical planning for low-metal-background requirements. Analytical support : HPLC, NMR, MS, and ICP-MS can be discussed according to project needs. Scale-up support : process optimization and batch-size planning after technical review.
概况
NH2 DOTA-GA (also known as 5-(2-aminoethylamino)-5-oxo-2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]pentanoic acid) (CAS 1639843-65-4, MF C21H38N6O9, MW 518.57) is a DOTA-family macrocyclic chelator building block used in radiopharmaceutical and metal-conjugate research. Programs working with this compound typically focus on selective functionalisation, radiometal compatibility (e.g., ⁹⁰Y, ¹⁷⁷Lu, ⁶⁴Cu), and conjugate stability. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.
应用
- NH2 DOTA-GA (1639843-65-4) supply and analog preparation for research programs
- Custom synthesis of mono-functionalised DOTA derivatives
- Trace-metal control studies for radiopharmaceutical conjugates
- Antibody and peptide radiolabeling research