Oligonucleotide Synthesis, RNA Raw Materials & Modification

2'-Deoxyguanosine Monohydrate

2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;hydrate

产品编号CH64003CAS号312693-72-4纯度99.4% (HPLC)

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产品概述

快速信息

产品系列: Oligonucleotide Synthesis, RNA Raw Materials & Modification
化学名称: 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;hydrate
分子式: C10H15N5O5
分子量: 285.26
纯度: 99.4% (HPLC)

2'-Deoxyguanosine monohydrate is the hydrated dGuo form of the purine DNA nucleoside, with guanine linked to 2-deoxy-β-D-ribose. CH64003 is listed under CAS 312693-72-4, molecular formula C10H15N5O5, molecular weight 285.26, and PubChem CID 135445705.

Keep this monohydrate record separate from anhydrous 2'-deoxyguanosine, which is cataloged separately as CH64008. In nucleoside research, deoxyguanosine is used as a deoxyguanosine-kinase substrate and as the canonical dG reference for purine DNA nucleoside chemistry.

同义词

2'-Deoxyguanosine monohydrate; dGuo monohydrate; 2'-deoxyriboguanosine hydrate

身份与规格

Catalog No.	CH64003
CAS No.	312693-72-4
Molecular Formula	C10H15N5O5 (monohydrate)
Molecular Weight	285.26 (monohydrate)
PubChem CID	135445705
InChIKey	LZSCQUCOIRGCEJ-FPKZOZHISA-N
Purity	99.4% (HPLC)

储存条件

-20 C

技术属性

Nucleobase: Guanine
Sugar: 2'-Deoxyribose
Nucleoside class: Purine 2'-deoxyribonucleoside
Material form: Monohydrate
Packaging: Custom packaging on request
Water content: Karl Fischer 6.1% w/w
Physical form: Solid
Stability: >=4 years

应用背景

Salvage-pathway phosphorylation research: literature reports deoxyguanosine as a substrate of deoxyguanosine kinase (dGK).
Purine DNA nucleoside reference: CH64003 provides the monohydrate dG identity for nucleoside and oligonucleotide chemistry comparisons.

公开来源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem 化合物 135445705
PubChem · CID 135445705

常见问题

Is CH64003 the monohydrate or anhydrous form?

It is the monohydrate (CAS 312693-72-4, C10H15N5O5, MW 285.26). The anhydrous 2'-deoxyguanosine (CAS 961-07-9) is listed as a separate CHEMOS product.

How is deoxyguanosine used in kinase research?

It is phosphorylated by deoxyguanosine kinase (dGK) in the nucleoside salvage pathway, so it serves as a defined purine deoxynucleoside substrate in phosphorylation studies.