Oligonucleotide Synthesis, RNA Raw Materials & Modification

2'-Deoxyadenosine (anhydrous)

(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

产品编号CH64007CAS号958-09-8纯度>98.0% (HPLC, titration)

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产品概述

快速信息

产品系列: Oligonucleotide Synthesis, RNA Raw Materials & Modification
化学名称: (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
分子式: C10H13N5O3
分子量: 251.24
纯度: >98.0% (HPLC, titration)

2'-Deoxyadenosine is the anhydrous dAdo form of the purine DNA nucleoside, with adenine linked to 2-deoxy-β-D-ribose. CH64007 is identified by CAS 958-09-8, molecular formula C10H13N5O3, molecular weight 251.24, and PubChem CID 13730.

Keep this record separate from 2'-deoxyadenosine monohydrate, which is listed separately as CH64001. In research literature, 2'-deoxyadenosine appears as a deoxynucleoside-kinase substrate and as the natural dA reference in polymerase and nucleoside-chemistry studies.

同义词

2'-Deoxyadenosine; deoxyadenosine; dAdo; dA (nucleoside)

身份与规格

Catalog No.	CH64007
CAS No.	958-09-8
Molecular Formula	C10H13N5O3 (anhydrous)
Molecular Weight	251.24 (anhydrous)
PubChem CID	13730
InChIKey	OLXZPDWKRNYJJZ-RRKCRQDMSA-N
Purity	>98.0% (HPLC, titration)

储存条件

0-10 C

技术属性

Nucleobase: Adenine
Sugar: 2'-Deoxyribose
Nucleoside class: Purine 2'-deoxyribonucleoside
Material form: Anhydrous
Packaging: Custom packaging on request
Physical form: Solid; white to almost white powder to crystal

应用背景

Kinase phosphorylation research: literature reports 2'-deoxyadenosine as a substrate for deoxycytidine kinase and adenosine kinase.
Polymerase building-block studies: modified dA building blocks are compared against the natural deoxyribonucleoside scaffold during polymerase-incorporation research.
Purine DNA nucleoside reference: CH64007 provides the anhydrous dAdo identity for nucleoside and oligonucleotide chemistry comparisons.

公开来源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem 化合物 13730
PubChem · CID 13730

常见问题

Is CH64007 the anhydrous or monohydrate form?

It is the anhydrous form (CAS 958-09-8, C10H13N5O3, MW 251.24). The monohydrate 2'-deoxyadenosine (CAS 16373-93-6) is listed as a separate CHEMOS product.

How is 2'-deoxyadenosine used as a kinase substrate?

It is phosphorylated by deoxycytidine kinase and adenosine kinase, so it is used as a defined purine deoxynucleoside substrate in phosphorylation research.