Oligonucleotide Synthesis, RNA Raw Materials & Modification

2'-Deoxyguanosine (anhydrous)

2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

产品编号CH64008CAS号961-07-9纯度>99.0% (HPLC)

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产品概述

快速信息

产品系列: Oligonucleotide Synthesis, RNA Raw Materials & Modification
化学名称: 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
分子式: C10H13N5O4
分子量: 267.24
纯度: >99.0% (HPLC)

2'-Deoxyguanosine is the anhydrous dGuo form of the purine DNA nucleoside, with guanine linked to 2-deoxy-β-D-ribose. CH64008 is identified by CAS 961-07-9, molecular formula C10H13N5O4, molecular weight 267.24, and PubChem CID 135398592.

Keep this record separate from CH64003, the monohydrate 2'-deoxyguanosine entry. The supported use context is research-facing: dGuo appears as a deoxyguanosine-kinase substrate in salvage-phosphorylation studies and as a canonical purine 2'-deoxyribonucleoside reference in nucleoside chemistry.

同义词

2'-Deoxyguanosine; deoxyguanosine; dGuo; dG (nucleoside)

身份与规格

Catalog No.	CH64008
CAS No.	961-07-9
Molecular Formula	C10H13N5O4 (anhydrous)
Molecular Weight	267.24 (anhydrous)
PubChem CID	135398592
InChIKey	YKBGVTZYEHREMT-KVQBGUIXSA-N
Purity	>99.0% (HPLC)

储存条件

Room temperature; cool and dark place below 15 C; inert gas

技术属性

Nucleobase: Guanine
Sugar: 2'-Deoxyribose
Nucleoside class: Purine 2'-deoxyribonucleoside
Material form: Anhydrous
Packaging: 1 g glass bottle with plastic insert; Custom packaging on request
Water content: <=10.0%
Physical form: Solid; white to almost white powder to crystal

应用背景

Deoxyguanosine kinase substrate: dGuo is used as the defined purine deoxynucleoside substrate in deoxyguanosine-kinase salvage-phosphorylation research.
Purine DNA nucleoside reference: CH64008 provides the anhydrous dGuo identity for nucleoside and oligonucleotide chemistry comparisons.

公开来源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem 化合物 135398592
PubChem · CID 135398592

常见问题

Is CH64008 the anhydrous or monohydrate form?

It is the anhydrous form (CAS 961-07-9, C10H13N5O4, MW 267.24). The monohydrate 2'-deoxyguanosine (CAS 312693-72-4) is listed as a separate CHEMOS product.

How is deoxyguanosine used in kinase research?

It is phosphorylated by deoxyguanosine kinase (dGK) in the nucleoside salvage pathway, so it serves as a defined purine deoxynucleoside substrate in phosphorylation studies.