Oligonucleotide Synthesis, RNA Raw Materials & Modification

Inosine

9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

产品编号CH64013CAS号58-63-9纯度100.0% (HPLC)

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产品概述

快速信息

产品系列: Oligonucleotide Synthesis, RNA Raw Materials & Modification
化学名称: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
分子式: C10H12N4O5
分子量: 268.23
纯度: 100.0% (HPLC)

Inosine is the purine RNA nucleoside with hypoxanthine linked to β-D-ribose. CH64013 is identified by CAS 58-63-9, molecular formula C10H12N4O5, molecular weight 268.23, and PubChem CID 135398641. It is the ribose counterpart of 2'-deoxyinosine, which is cataloged separately as CH64006.

The supported research context is PNP enzymology and RNA nucleoside chemistry: inosine is a purine nucleoside phosphorylase substrate and a hypoxanthine ribonucleoside reference.

同义词

Inosine; hypoxanthine riboside; Ino

身份与规格

Catalog No.	CH64013
CAS No.	58-63-9
Molecular Formula	C10H12N4O5
Molecular Weight	268.23
PubChem CID	135398641
InChIKey	UGQMRVRMYYASKQ-KQYNXXCUSA-N
Purity	100.0% (HPLC)

储存条件

-20 C

技术属性

Nucleobase: Hypoxanthine
Sugar: D-Ribose
Nucleoside class: Purine ribonucleoside
Packaging: Custom packaging on request
Physical form: Solid
Stability: >=4 years

应用背景

Purine nucleoside phosphorylase substrate: inosine is used as a defined substrate in PNP structural and enzymology research.
Purine RNA nucleoside reference: CH64013 provides the hypoxanthine ribonucleoside identity for RNA and nucleoside chemistry comparisons.

公开来源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem 化合物 135398641
PubChem · CID 135398641

常见问题

Is CH64013 the RNA or DNA nucleoside?

It is inosine, the RNA (ribo) nucleoside. The DNA counterpart, 2'-deoxyinosine, is listed separately by CHEMOS.

How is inosine used in enzyme research?

Inosine is a substrate of purine nucleoside phosphorylase (PNP), which phosphorolyzes it to hypoxanthine and ribose-1-phosphate, so it serves as a reference substrate in PNP enzymology.