Oligonucleotide Synthesis, RNA Raw Materials & Modification

7-Deaza-2'-deoxyguanosine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

产品编号CH64046CAS号86392-75-8纯度>=98.0%

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产品概述

快速信息

产品系列: Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式: C11H14N4O4
分子量: 266.25
纯度: >=98.0%

7-Deaza-2'-deoxyguanosine (c7dG) is 2'-deoxyguanosine in which the purine N7 nitrogen is replaced by carbon, giving a pyrrolo[2,3-d]pyrimidine base. CH64046 is identified by CAS 86392-75-8, molecular formula C11H14N4O4, molecular weight 266.25, and PubChem CID 135411006.

The cited oligonucleotide literature discusses 7-deaza-dG analogs in base-pairing, duplex-stability, and sequencing band-compression studies where the purine N7 position is being evaluated.

同义词

7-Deaza-2'-deoxyguanosine; c7dG; 7-deaza-dG

身份与规格

Catalog No.	CH64046
CAS No.	86392-75-8
Molecular Formula	C11H14N4O4
Molecular Weight	266.25
PubChem CID	135411006
InChIKey	PFCLMNDDPTZJHQ-XLPZGREQSA-N
Purity	>=98.0%

储存条件

2-8 C; keep dark and dry

技术属性

Nucleobase analog: 7-Deazaguanine
Sugar: 2'-Deoxyribose
Base modification: 7-Deaza (N7 replaced by carbon)
Research role: Modified-oligonucleotide building-block reference
Packaging: 100 mg; 250 mg; 1 g; 5 g; Custom packaging on request
Physical form: White to off-white powder

应用背景

7-Deazapurine oligonucleotide research: CH64046 is relevant to base-pairing, duplex-stability, and sequencing band-compression studies involving the N7→C base modification.
N7-position interaction studies: the 7-deaza base supports comparison of DNA systems where Hoogsteen contacts or metal-binding behavior at the purine N7 position is being evaluated.
Base-analog reference: CH64046 provides the 7-deaza-2'-deoxyguanosine identity for nucleoside chemistry research.

公开来源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem 化合物 135411006
PubChem · CID 135411006

常见问题

What is different about 7-deaza-2'-deoxyguanosine?

The purine N7 nitrogen is replaced by carbon, giving a 7-deazapurine base. This allows comparison of systems where the purine N7 position is relevant to Hoogsteen pairing, metal binding, or sequencing band compression.