5-TFA-aa-Uridine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
产品概述
快速信息
- 产品系列
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 分子式
- C14H16F3N3O7
- 分子量
- 395.29
- 纯度
- >98.00%
5-TFA-aa-Uridine is uridine carrying an aminoallyl amino-linker at the C5 position of uracil, with the linker's terminal amine protected as a trifluoroacetamide (TFA). CH64057 is identified by CAS 869222-68-4, molecular formula C14H16F3N3O7, molecular weight 395.29, PubChem CID 71463691, and InChIKey DMXZSDJKAIYXMV-TVIFIVJDSA-N.
The aminoallyl arm provides a protected amine-linker motif on a ribonucleoside. The cited labeling literature discusses amine-linker nucleosides in covalent fluorophore attachment and indirect labeling research for nucleic acids.
同义词
5-(trifluoroacetamidoallyl)uridine; 5-TFA-aa-U; TFA-aminoallyl-uridine
身份与规格
| Catalog No. | CH64057 |
| CAS No. | 869222-68-4 |
| Molecular Formula | C14H16F3N3O7 |
| Molecular Weight | 395.29 |
| PubChem CID | 71463691 |
| InChIKey | DMXZSDJKAIYXMV-TVIFIVJDSA-N |
| Purity | >98.00% |
储存条件
2-8 C, away from moisture
技术属性
- Nucleobase
- Uracil
- Sugar
- D-Ribose
- C5 linker
- Aminoallyl
- Amine protection
- Trifluoroacetyl (TFA)
- Packaging
- 50 mg; 100 mg; 250 mg; 1 g; Custom packaging on request
应用背景
- Aminoallyl labeling research: CH64057 combines a uridine identity with a C5 TFA-protected aminoallyl linker for indirect nucleic-acid labeling studies.
- Amine-linker labeling studies: the TFA-protected aminoallyl group represents a protected amine-linker motif discussed for covalent fluorophore attachment after deprotection.
- Base-analog reference: CH64057 provides the 5-TFA-aa-uridine identity for nucleoside chemistry research.
相关技术资源
公开来源
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem 化合物 71463691
PubChem · CID 71463691
常见问题
What does 'aa' (aminoallyl) mean here?
'aa' is the aminoallyl linker, a 3-aminoprop-1-enyl arm at the C5 position. Its terminal amine is protected as a trifluoroacetamide (TFA).
Is this the RNA or DNA nucleoside?
It is a uridine (ribonucleoside). The 2'-deoxy aminoallyl versions (dU, dC) are cataloged separately.
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