N4-Benzoyl-2'-deoxycytidine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
产品概述
快速信息
- 产品系列
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 分子式
- C16H17N3O5
- 分子量
- 331.32
- 纯度
- >98.0% (HPLC)
N4-Benzoyl-2'-deoxycytidine (dCBz) is 2'-deoxycytidine whose cytosine exocyclic N4-amine is protected with a benzoyl group. CH64073 is identified by CAS 4836-13-9, molecular formula C16H17N3O5, molecular weight 331.32, PubChem CID 9797617, and InChIKey MPSJHJFNKMUKCN-OUCADQQQSA-N.
The cited oligonucleotide-synthesis literature discusses exocyclic-amine protecting groups on nucleobases and their removal during deprotection. CH64073 provides the N4-benzoyl-protected 2'-deoxycytidine identity for DNA building-block and nucleoside chemistry research.
同义词
N4-Benzoyl-2'-deoxycytidine; N4-Bz-dC; dCBz
身份与规格
| Catalog No. | CH64073 |
| CAS No. | 4836-13-9 |
| Molecular Formula | C16H17N3O5 |
| Molecular Weight | 331.32 |
| PubChem CID | 9797617 |
| InChIKey | MPSJHJFNKMUKCN-OUCADQQQSA-N |
| Purity | >98.0% (HPLC) |
储存条件
-20 C
技术属性
- Nucleobase
- Cytosine
- Sugar
- 2'-Deoxyribose
- Base protection
- N4-Benzoyl
- Synthesis role
- Base-protected DNA nucleoside intermediate
- Packaging
- 100 mg; 1 g; Custom packaging on request
- Physical form
- solid
- Stability
- >=4 years
应用背景
- Base-protected DNA building block: the N4-benzoyl group masks the cytosine exocyclic amine in oligonucleotide-synthesis chemistry and is removed during deprotection.
- Cytosine (dC) monomer precursor context: CH64073 is the base-protected 2'-deoxycytidine identity relevant to cytosine building-block preparation.
- Nucleoside chemistry reference: CH64073 provides the N4-benzoyl-2'-deoxycytidine (dCBz) identity for nucleoside chemistry research.
相关技术资源
公开来源
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem 化合物 9797617
PubChem · CID 9797617
常见问题
Why is the N4-amine of this deoxycytidine benzoylated?
In oligonucleotide synthesis the reactive exocyclic amine of cytosine is masked with a protecting group such as benzoyl to prevent side reactions; the benzoyl group is later removed during deprotection.
How does it differ from 2'-deoxycytidine?
It carries a benzoyl group on the cytosine N4-amine, whereas 2'-deoxycytidine is unprotected. 2'-deoxycytidine is cataloged separately.
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