5-aa-UTP (Aminoallyl-UTP)
Oligonucleotide Synthesis, RNA Raw Materials & Modification
产品概述
快速信息
- 产品系列
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 纯度
- >95% (HPLC, UV)
5-aa-UTP is 5-(3-aminoallyl)-uridine-5'-triphosphate, commonly described as aminoallyl-UTP. It is an amine-modified ribonucleotide triphosphate and the UTP counterpart of aminoallyl-dUTP. Key identifiers for this catalog entry are CHEMOS CH66012 and CAS 75221-88-4.
In enzymatic RNA labeling workflows, aminoallyl-UTP can be incorporated during in vitro transcription to introduce a primary amine into RNA. The amine can then react with amine-reactive reporters such as NHS-ester dyes, enabling post-synthetic transcript labeling. This page keeps the identity boundary to the supplier catalog name, CAS number, and literature-supported aminoallyl-UTP use context.
同义词
aminoallyl-UTP; 5-(3-aminoallyl)-uridine-5'-triphosphate; AA-UTP
身份与规格
| Catalog No. | CH66012 |
| Product Name | 5-aa-UTP (Aminoallyl-UTP) |
| CAS No. | 75221-88-4 |
| Product Type | Amine-modified ribonucleotide triphosphate |
| Labeling Handle | 5-aminoallyl primary amine |
| Purity | >95% (HPLC, UV) |
储存条件
freeze below -15 C; minimize light exposure
技术属性
- Nucleotide class
- rNTP
- Parent nucleotide
- UTP
- Base modification
- 5-(3-Aminoallyl)
- Reactive handle
- Primary amine
- Packaging
- 1 mg; 5 mg; 50 µL; 100 µL; 250 µL; 5 µmol; 5 x 5 umol; 5 x 50 uL; Custom packaging on request
- Solution concentration
- 4 mM
- Physical form
- aqueous solution
- Stability
- 6 months upon receiving
应用背景
- Amine handle in RNA: used as an aminoallyl-modified UTP to introduce a primary amine during in vitro transcription.
- Post-synthetic labeling: the aminoallyl handle can react with amine-reactive reporters such as NHS-ester dyes.
- Ribonucleotide labeling: serves as the RNA-labeling counterpart to aminoallyl-dUTP.
相关技术资源
公开来源
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
常见问题
What is 5-aa-UTP used for?
5-aa-UTP is an aminoallyl-modified UTP used to introduce a primary amine into RNA during in vitro transcription for post-synthetic labeling.
How does it differ from aminoallyl-dUTP?
5-aa-UTP is the ribonucleotide version for RNA labeling, while aminoallyl-dUTP is the deoxyribonucleotide version for DNA labeling.
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