Oligonucleotide Synthesis, RNA Raw Materials & Modification

2'-FANA-Inosine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

产品编号CH70040CAS号98983-40-5纯度>=98%

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产品概述

快速信息

产品系列: Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式: C10H11FN4O4
分子量: 270.22
纯度: >=98%

2'-FANA-Inosine is a 2'F-ANA modified nucleoside: inosine (hypoxanthine base) attached to a 2'-deoxy-2'-fluoro-beta-D-arabinofuranose sugar. Key identifiers include CAS 98983-40-5, molecular formula C10H11FN4O4, and molecular weight 270.22 (PubChem CID 135778987).

The 2'F-ANA family uses an arabino C2' configuration, which distinguishes it from ribo 2'-F-RNA. CH70040 should be presented as a modified nucleoside/reference compound for structure and catalog matching, not as a protected CE phosphoramidite monomer.

同义词

2'-deoxy-2'-fluoroarabino inosine; 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl inosine

身份与规格

Catalog No.	CH70040
CAS No.	98983-40-5
Molecular Formula	C10H11FN4O4
Molecular Weight	270.22
PubChem CID	135778987
InChIKey	NRVOTDBYJXFINS-GQTRHBFLSA-N
Purity	>=98%

储存条件

4 C under nitrogen; -80 C or -20 C in solvent under nitrogen

技术属性

Material class: 2'F-ANA nucleoside
Nucleobase: Hypoxanthine
Sugar configuration: 2'-Deoxy-2'-fluoro-beta-D-arabinofuranose
Protection state: Unprotected
Packaging: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 250 mg; 500 mg; 1 g; Custom packaging on request
Physical form: White to off-white solid
Stability: 6 months at -80 C or 1 month at -20 C in solvent

应用背景

2'F-ANA nucleoside reference: a hypoxanthine-bearing 2'-deoxy-2'-fluoroarabino nucleoside for modified-nucleic-acid research.
Arabino 2'-fluoro chemistry: the arabino C2' configuration distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.
Oligonucleotide chemistry context: use the 2'F-ANA class name and identifiers when matching research catalog records or confirmed internal specifications.

公开来源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem 化合物 135778987
PubChem · CID 135778987

常见问题

What is 2'-FANA-Inosine?

2'-FANA-Inosine is a 2'-deoxy-2'-fluoroarabino inosine modified nucleoside. Its hypoxanthine base and arabino-configured 2'-fluoro sugar are confirmed by PubChem CID 135778987.

How is 2'F-ANA different from ribo 2'-F-RNA?

Both contain a 2'-fluoro sugar modification, but 2'F-ANA has the arabino configuration at C2'. That stereochemical difference distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.

Is CH70040 a phosphoramidite monomer?

No. CH70040 is documented as the modified nucleoside 2'-FANA-Inosine. A protected CE phosphoramidite would require separate structural evidence and identifiers.