Oligonucleotide Synthesis, RNA Raw Materials & Modification

2'-FANA-uridine

1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

产品编号CH70041CAS号69123-94-0纯度98.36%

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产品概述

快速信息

产品系列: Oligonucleotide Synthesis, RNA Raw Materials & Modification
化学名称: 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
分子式: C9H11FN2O5
分子量: 246.19
纯度: 98.36%

2'-FANA-uridine is a 2'F-ANA modified nucleoside: uridine attached to a 2'-deoxy-2'-fluoro-beta-D-arabinofuranose sugar. Key identifiers include CAS 69123-94-0, molecular formula C9H11FN2O5, molecular weight 246.19, and PubChem CID 3007908.

The 2'F-ANA family uses an arabino C2' configuration, which distinguishes it from ribo 2'-F-RNA. CH70041 should be presented as a modified nucleoside/reference compound for structure and catalog matching, not as a protected CE phosphoramidite monomer.

同义词

2'-deoxy-2'-fluoro-arabino uridine; 2'F-ANA uridine

身份与规格

Catalog No.	CH70041
CAS No.	69123-94-0
Molecular Formula	C9H11FN2O5
Molecular Weight	246.19
Exact Mass	246.06519962
PubChem CID	3007908
InChIKey	UIYWFOZZIZEEKJ-PXBUCIJWSA-N
Purity	98.36%

储存条件

-20 C or 4 C for powder; -80 C or -20 C in solvent

技术属性

Material class: 2'F-ANA nucleoside
Nucleobase: Uracil
Sugar configuration: 2'-Deoxy-2'-fluoro-beta-D-arabinofuranose
Protection state: Unprotected
Packaging: 100 mg; 200 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 10 mM x 1 mL in DMSO; Custom packaging on request
Solution concentration: 10 mM in DMSO
Physical form: Solid
Stability: 3 years at -20 C or 2 years at 4 C for powder; 6 months at -80 C or 1 month at -20 C in solvent

应用背景

2'F-ANA nucleoside reference: a uridine-bearing 2'-deoxy-2'-fluoroarabino nucleoside for modified-nucleic-acid research.
Arabino 2'-fluoro chemistry: the arabino C2' configuration distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.
Oligonucleotide chemistry context: use the 2'F-ANA class name and identifiers when matching research catalog records or confirmed internal specifications.

公开来源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem 化合物 3007908
PubChem · CID 3007908

常见问题

What is 2'-FANA-uridine?

2'-FANA-uridine is a 2'-deoxy-2'-fluoroarabino uridine modified nucleoside. Its uridine base and arabino-configured 2'-fluoro sugar are confirmed by PubChem CID 3007908.

How is 2'F-ANA different from ribo 2'-F-RNA?

Both contain a 2'-fluoro sugar modification, but 2'F-ANA has the arabino configuration at C2'. That stereochemical difference distinguishes 2'F-ANA nucleosides from ribo 2'-F-RNA analogues.

Is CH70041 a phosphoramidite monomer?

No. CH70041 is documented as the modified nucleoside 2'-FANA-uridine. A protected CE phosphoramidite would require separate structural evidence and identifiers.