5'-O-DMT-2'-O-TBDMS-N1-methyl-pseudouridine
5-[(2S,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-1-methylpyrimidine-2,4-dione
产品概述
快速信息
- 产品系列
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 化学名称
- 5-[(2S,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-1-methylpyrimidine-2,4-dione
- 分子式
- C37H46N2O8Si
- 分子量
- 674.9
- 纯度
- >=98.0% (HPLC)
5'-O-DMT-2'-O-TBDMS-N1-methyl-pseudouridine is catalog CH70331. PubChem resolves CAS 875302-41-3 to CID 67259612, with molecular formula C37H46N2O8Si, molecular weight 674.9, exact mass 674.30234296, and InChIKey LAUAFECHUGXCAW-NXVJRICRSA-N.
This entry describes a protected N1-methylpseudouridine nucleoside bearing 5'-O-DMT and 2'-O-TBDMS groups. It is distinct from the corresponding CE phosphoramidite derivative and is positioned here for modified-nucleoside synthesis research and structure matching.
同义词
5'-O-(4,4'-Dimethoxitrityl)-2'-O-(tert-butyldimethylsilyl)-1-N-methylpseudouridine; 5'-O-DMT-2'-O-TBDMS-N1-methyl-pseudouridine (source name)
身份与规格
| Catalog No. | CH70331 |
| Product Name | 5'-O-DMT-2'-O-TBDMS-N1-methyl-pseudouridine |
| CAS No. | 875302-41-3 |
| Molecular Formula | C37H46N2O8Si |
| Molecular Weight | 674.9 |
| Exact Mass | 674.30234296 |
| PubChem CID | 67259612 |
| InChIKey | LAUAFECHUGXCAW-NXVJRICRSA-N |
| Synonyms | 5'-O-DMT-2'-O-TBDMS-N1-methylpseudouridine; protected N1-methylpseudouridine nucleoside; CAS 875302-41-3 |
| Purity | >=98.0% (HPLC) |
储存条件
-15 to -25 C
技术属性
- Material class
- Protected N1-methylpseudouridine
- Nucleoside identity
- N1-Methylpseudouridine
- 2'-O protection
- TBDMS
- 5'-O protection
- DMT
- Packaging
- Custom packaging on request
应用背景
- Protected nucleoside intermediate: CAS 875302-41-3 and PubChem CID 67259612 support a 5'-O-DMT, 2'-O-TBDMS, N1-methylpseudouridine protected nucleoside identity.
- DMT/TBDMS-protected derivative work: the DMT and TBDMS protecting groups make this entry relevant to research workflows that require protected N1-methylpseudouridine derivatives.
- Derivative distinction: formula C37H46N2O8Si and InChIKey LAUAFECHUGXCAW-NXVJRICRSA-N help distinguish CH70331 from CE phosphoramidite derivatives.
补充物料信息
用途
Use this catalog entry for research-oriented identity matching, protected pseudouridine derivative work, and catalog searches involving DMT/TBDMS-protected N1-methylpseudouridine.
特性
5'-O-DMT-2'-O-TBDMS-N1-methyl-pseudouridine is represented here as a protected modified nucleoside. Use the CAS number, PubChem CID, formula, exact mass, and InChIKey when aligning this entry with product specifications.
相关技术资源
公开来源
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem 化合物 67259612
PubChem · CID 67259612
常见问题
What is 5'-O-DMT-2'-O-TBDMS-N1-methyl-pseudouridine?
It is catalog CH70331. PubChem resolves CAS 875302-41-3 to CID 67259612, with formula C37H46N2O8Si and molecular weight 674.9.
Is CH70331 the same as the CE phosphoramidite derivative?
No. CH70331 is the protected nucleoside identity for CAS 875302-41-3. The CE phosphoramidite derivative has a different CAS, formula, and structure.
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