Azetidin-3-ol hydrochloride

Azetidin-3-ol hydrochloride

化学名称

azetidin-3-ol;hydrochloride

Azetidin-3-ol hydrochlorideADC linker
Structure: Azetidin-3-ol hydrochloride structure, CAS 18621-18-6, MW 109.55
产品编号
CH53010
CAS
18621-18-6
分子式
C3H8ClNO
分子量
109.55
规格标准
Catalog No.CH53010
CAS No.18621-18-6
Molecular FormulaC3H8ClNO
Molecular Weight109.55

品类工艺支持

CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.

概况

Azetidin-3-ol hydrochloride (also known as azetidin-3-ol;hydrochloride) (CAS 18621-18-6, MF C3H8ClNO, MW 109.55) is used as a linker / reactive-handle building block in ADC and bioconjugation research. Programs working with this compound usually examine selectivity of the bioconjugation chemistry, linker stability, and downstream payload release. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

应用

  • Azetidin-3-ol hydrochloride (18621-18-6) as a starting point for downstream chemistry programs
  • Process-development support for scalable linker preparation
  • Bioconjugation handle for site-specific cysteine / lysine attachment
  • Click-chemistry coupling (DBCO / azide) for bioconjugation programs

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