Azetidine-3-carboxylic acid

Azetidine-3-carboxylic acid

Azetidine-3-carboxylic acidADC linker
Structure: Azetidine-3-carboxylic acid structure, CAS 36476-78-5, MW 101.1
产品编号
CH53012
CAS
36476-78-5
分子式
C4H7NO2
分子量
101.1
规格标准
Catalog No.CH53012
CAS No.36476-78-5
Molecular FormulaC4H7NO2
Molecular Weight101.1

品类工艺支持

CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.

概况

Azetidine-3-carboxylic acid (CAS 36476-78-5, MF C4H7NO2, MW 101.1) is used as a linker / reactive-handle building block in ADC and bioconjugation research. Programs working with this compound usually examine selectivity of the bioconjugation chemistry, linker stability, and downstream payload release. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.

应用

  • Azetidine-3-carboxylic acid (CAS 36476-78-5) route review and custom analog preparation
  • Process-development support for scalable linker preparation
  • Antibody-drug conjugate (ADC) linker chemistry research
  • Bioconjugation handle for site-specific cysteine / lysine attachment

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