Sulfo-SMCC sodium
化学名称
sodium 1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
Sulfo-SMCC sodium•ADC linker
Structure: 
产品编号
CH53019
CAS
92921-24-9
分子式
C16H17N2NaO9S
分子量
438.38
规格标准
| Catalog No. | CH53019 |
| CAS No. | 92921-24-9 |
| Molecular Formula | C16H17N2NaO9S |
| Molecular Weight | 438.38 |
品类工艺支持
CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.
概况
Sulfo-SMCC sodium (also known as sodium 1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate) (CAS 92921-24-9, MF C16H17N2NaO9S, MW 438.38) belongs to the ADC linker / bioconjugation handle class. Practical chemistry questions involve the conjugation chemistry, peptide-cleavable element design (where applicable), and analytical control of related impurities. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.
应用
- Sulfo-SMCC sodium (92921-24-9) supply and analog preparation for research programs
- Click-chemistry coupling (DBCO / azide) for bioconjugation programs
- Process-development support for scalable linker preparation
- Bioconjugation handle for site-specific cysteine / lysine attachment