DSPE-PEG2000-Mal

DSPE-PEG2000-Mal

화학명

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium

DSPE-PEG2000-MalLNP
Structure: DSPE-PEG2000-Mal structure, CAS 474922-22-0, MW 2000 (Average)
제품 번호
CH51020
CAS
474922-22-0
분자식
(C2H4O)nC51H92NO13P.H3N
분자량
2000 (Average)
사양
Catalog No.CH51020
CAS No.474922-22-0
Molecular Formula(C2H4O)nC51H92NO13P.H3N
Molecular Weight2000 (Average)

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

개요

DSPE-PEG2000-Mal (also known as 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium) (CAS 474922-22-0, MF (C2H4O)nC51H92NO13P.H3N, MW 2000 (Average)) belongs to the PEGylated lipid class used in LNP and liposome research. Programs typically discuss polydispersity of the PEG segment, lipid-anchor connectivity, and the terminal-group handle available for downstream conjugation. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.

응용

  • DSPE-PEG2000-Mal (474922-22-0) supply and analog preparation for research programs
  • Process-development support for scalable PEG-lipid preparation
  • Analytical method development for PEG-lipid characterisation
  • Stealth or functional PEG-lipid component in LNP / liposomal formulation research

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