DOTA-tri(t-butyl ester)
화학명
2-[4,7,10-tris[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
DOTA-tri(t-butyl ester)•DOTA
Structure: 
제품 번호
CH54001
CAS
137076-54-1
분자식
C28H52N4O8
분자량
572.73
사양
| Catalog No. | CH54001 |
| CAS No. | 137076-54-1 |
| Molecular Formula | C28H52N4O8 |
| Molecular Weight | 572.73 |
CHEMOS Support for This Category
CHEMOS supports DOTA chelator and radiopharmaceutical building-block chemistry, including protected, activated, PEG-spaced, and conjugation-ready intermediates. DOTA and DOTA-GA derivatives : protected chelators, activated esters, maleimide derivatives, and linker-spaced variants. Custom chelator-linker synthesis : route design for chelator-linker-targeting moiety intermediates. Metal-sensitive process control : purification and analytical planning for low-metal-background requirements. Analytical support : HPLC, NMR, MS, and ICP-MS can be discussed according to project needs. Scale-up support : process optimization and batch-size planning after technical review.
개요
DOTA-tri(t-butyl ester) (also known as 2-[4,7,10-tris[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid) (CAS 137076-54-1, MF C28H52N4O8, MW 572.73) belongs to the DOTA-family chelator class for targeted radiopharmaceutical research. Programs typically examine residual metal control, kinetic inertness of the metal complex, and the available coupling handle. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
응용
- DOTA-tri(t-butyl ester) (CAS 137076-54-1) route review and custom analog preparation
- Process-development support for scalable chelator preparation
- Targeted radioligand therapy (TRT) building block — ⁹⁰Y / ¹⁷⁷Lu / ²²⁵Ac conjugates
- DOTA-conjugate analog synthesis (e.g., DOTATATE-family research)