Bis(2-bromoethyl) ether
화학명
1-bromo-2-(2-bromoethoxy)ethane
Bis(2-bromoethyl) ether•PROTAC
Structure: 
제품 번호
CH56002
CAS
5414-19-7
분자식
C4H8Br2O
분자량
231.91
사양
| Catalog No. | CH56002 |
| CAS No. | 5414-19-7 |
| Molecular Formula | C4H8Br2O |
| Molecular Weight | 231.91 |
CHEMOS Support for This Category
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
개요
Bis(2-bromoethyl) ether (also known as 1-bromo-2-(2-bromoethoxy)ethane) (CAS 5414-19-7, MF C4H8Br2O, MW 231.91) is a PROTAC research building block — typically a linker, E3-ligase ligand, or degrader handle. Practical chemistry topics include orthogonal protecting groups, modular linker chemistry, and stereo-purity at chiral centres. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
응용
- Bis(2-bromoethyl) ether (CAS 5414-19-7) route review and custom analog preparation
- Reference material in targeted protein degradation chemistry programs
- PROTAC building block — linker / E3-ligand / degrader handle
- Bifunctional degrader synthesis with orthogonal protecting groups