N6-Benzoyladenosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
제품 개요
빠른 보기
- 제품군
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 분자식
- C17H17N5O5
- 분자량
- 371.35
- 순도
- >=98%
N6-Benzoyladenosine (rABz) is adenosine whose adenine exocyclic N6-amine is protected with a benzoyl group. CH64081 is identified by CAS 4546-55-8, molecular formula C17H17N5O5, molecular weight 371.35, PubChem CID 11728391, and InChIKey NZDWTKFDAUOODA-CNEMSGBDSA-N.
The cited oligonucleotide-synthesis literature discusses exocyclic-amine protecting groups on nucleobases and their removal during deprotection. CH64081 provides the N6-benzoyl-protected adenosine identity for RNA building-block and nucleoside chemistry research.
동의어
N6-Benzoyladenosine; N6-Bz-rA; rABz
식별 정보 및 규격
| Catalog No. | CH64081 |
| CAS No. | 4546-55-8 |
| Molecular Formula | C17H17N5O5 |
| Molecular Weight | 371.35 |
| PubChem CID | 11728391 |
| InChIKey | NZDWTKFDAUOODA-CNEMSGBDSA-N |
| Purity | >=98% |
보관 조건
Room temperature; recommended cool and dark below 15 C
기술 속성
- Nucleobase
- Adenine
- Sugar
- D-Ribose
- Base protection
- N6-Benzoyl
- Synthesis role
- Base-protected RNA nucleoside intermediate
- Packaging
- 1 g; 5 g; Custom packaging on request
- Water content
- <=8.0%
- Physical form
- solid; white to almost white powder to crystal
응용 맥락
- Base-protected RNA building block: the N6-benzoyl group masks the adenine exocyclic amine in RNA oligonucleotide-synthesis chemistry and is removed during deprotection.
- Adenosine (rA) monomer precursor context: CH64081 is the base-protected adenosine identity relevant to adenine building-block preparation.
- Nucleoside chemistry reference: CH64081 provides the N6-benzoyladenosine (rABz) identity for nucleoside chemistry research.
관련 기술 자료
공개 출처
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem 화합물 11728391
PubChem · CID 11728391
자주 묻는 질문
Why is the N6-amine of this adenosine benzoylated?
In RNA oligonucleotide synthesis the reactive exocyclic amine of adenine is masked with a protecting group such as benzoyl to prevent side reactions; the benzoyl group is later removed during deprotection.
How does it differ from N6-benzoyl-2'-deoxyadenosine?
Both carry an N6-benzoyl-protected adenine, but this one is the ribonucleoside (2'-OH), while N6-benzoyl-2'-deoxyadenosine is the 2'-deoxy form. Both are cataloged separately.
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