N4-Benzoylcytidine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
제품 개요
빠른 보기
- 제품군
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 분자식
- C16H17N3O6
- 분자량
- 347.32
- 순도
- 99%
N4-Benzoylcytidine (rCBz) is cytidine whose cytosine exocyclic N4-amine is protected with a benzoyl group. CH64082 is identified by CAS 13089-48-0, molecular formula C16H17N3O6, molecular weight 347.32, PubChem CID 10066259, and InChIKey BNXBRFDWSPXODM-BPGGGUHBSA-N.
The cited oligonucleotide-synthesis literature discusses exocyclic-amine protecting groups on nucleobases and their removal during deprotection. CH64082 provides the N4-benzoyl-protected cytidine identity for RNA building-block and nucleoside chemistry research.
동의어
N4-Benzoylcytidine; N4-Bz-rC; rCBz
식별 정보 및 규격
| Catalog No. | CH64082 |
| CAS No. | 13089-48-0 |
| Molecular Formula | C16H17N3O6 |
| Molecular Weight | 347.32 |
| PubChem CID | 10066259 |
| InChIKey | BNXBRFDWSPXODM-BPGGGUHBSA-N |
| Purity | 99% |
보관 조건
Room temperature; recommended cool and dark below 15 C; store under inert gas; hygroscopic
기술 속성
- Nucleobase
- Cytosine
- Sugar
- D-Ribose
- Base protection
- N4-Benzoyl
- Synthesis role
- Base-protected RNA nucleoside intermediate
- Packaging
- 1 g; 5 g; Custom packaging on request
- Physical form
- solid; white to almost white powder to crystal
응용 맥락
- Base-protected RNA building block: the N4-benzoyl group masks the cytosine exocyclic amine in RNA oligonucleotide-synthesis chemistry and is removed during deprotection.
- Cytidine (rC) monomer precursor context: CH64082 is the base-protected cytidine identity relevant to cytosine building-block preparation.
- Nucleoside chemistry reference: CH64082 provides the N4-benzoylcytidine (rCBz) identity for nucleoside chemistry research.
관련 기술 자료
공개 출처
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem 화합물 10066259
PubChem · CID 10066259
자주 묻는 질문
Why is the N4-amine of this cytidine benzoylated?
In RNA oligonucleotide synthesis the reactive exocyclic amine of cytosine is masked with a protecting group such as benzoyl to prevent side reactions; the benzoyl group is later removed during deprotection.
How does it differ from N4-benzoyl-2'-deoxycytidine?
Both carry an N4-benzoyl-protected cytosine, but this one is the ribonucleoside (2'-OH), while N4-benzoyl-2'-deoxycytidine is the 2'-deoxy form. Both are cataloged separately.
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