dUTP, 100 mM Solution
Oligonucleotide Synthesis, RNA Raw Materials & Modification
제품 개요
빠른 보기
- 제품군
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 순도
- 99.98%
dUTP, 100 mM Solution is 2'-deoxyuridine-5'-triphosphate (dUTP) listed as a 100 mM solution. Key identifiers include CAS 102814-08-4 and PubChem CID 65070. The PubChem record provides the stereospecific neutral-structure reference; the CHEMOS listing does not specify salt stoichiometry.
dUTP is a deoxynucleoside triphosphate carrying a uracil base. DNA polymerases catalyze the template-directed polymerization of dNTP substrates onto the 3'-end of a growing DNA primer strand, so dUTP supplies a uracil (U) residue during enzymatic DNA synthesis — for example in place of dTTP, in dUTP/uracil-DNA-glycosylase (UDG) carryover-prevention workflows, and in enzymatic labeling.
동의어
2'-deoxyuridine 5'-triphosphate; dUTP, 100 mM solution
식별 정보 및 규격
| Catalog No. | CH66005 |
| CAS No. | 102814-08-4 |
| Neutral Structure Formula | C9H15N2O14P3 |
| Neutral Structure MW | 468.14 |
| PubChem CID | 65070 |
| InChIKey | AHCYMLUZIRLXAA-SHYZEUOFSA-N |
| Concentration | 100 mM solution |
| Purity | 99.98% |
보관 조건
-20 C
기술 속성
- Nucleotide class
- dNTP
- Nucleobase
- Uracil
- 5'-phosphate state
- Triphosphate
- Grade
- PCR Grade
- Packaging
- 100 µL; 400 µL; 1 mL; 5 mL; 10 mL; 25 mL; 100 mL; Custom packaging on request
- Solution concentration
- 100 mM
- Physical form
- colorless transparent solution
- Stability
- 12 months
응용 맥락
- Uracil dNTP substrate: supplies a uracil (U) residue during enzymatic, template-directed DNA synthesis by DNA polymerases (in place of thymine).
- Carryover prevention & labeling: used in dUTP/uracil-DNA-glycosylase (UDG) carryover-prevention workflows and in enzymatic labeling reactions.
- Solution presentation: listed as a 100 mM solution.
관련 기술 자료
공개 출처
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem 화합물 65070
PubChem · CID 65070
자주 묻는 질문
What is dUTP used for?
dUTP is the uracil deoxynucleoside triphosphate. DNA polymerases can incorporate it in place of thymine during enzymatic DNA synthesis. It is commonly used in dUTP/uracil-DNA-glycosylase (UDG) carryover-prevention workflows and in enzymatic labeling.
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