Boc-NH-PEG2-C2-NH2
化学名称
tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
Boc-NH-PEG2-C2-NH2•PROTAC
Structure: 
产品编号
CH56001
CAS
153086-78-3
分子式
C11H24N2O4
分子量
248.32
规格标准
| Catalog No. | CH56001 |
| CAS No. | 153086-78-3 |
| Molecular Formula | C11H24N2O4 |
| Molecular Weight | 248.32 |
品类工艺支持
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概况
Boc-NH-PEG2-C2-NH2 (also known as tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate) (CAS 153086-78-3, MF C11H24N2O4, MW 248.32) belongs to the PROTAC building-block class (linker / E3 ligand / warhead). Programs working with this compound typically focus on coupling-handle compatibility, linker length / composition exploration, and impurity control. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.
应用
- Boc-NH-PEG2-C2-NH2 (CAS 153086-78-3) route review and custom analog preparation
- Reference material in targeted protein degradation chemistry programs
- PROTAC building block — linker / E3-ligand / degrader handle
- Bifunctional degrader synthesis with orthogonal protecting groups