Hexane-1,6-diol
Hexane-1,6-diol•PROTAC
Structure: 
产品编号
CH56005
CAS
629-11-8
分子式
C6H14O2
分子量
118.17
规格标准
| Catalog No. | CH56005 |
| CAS No. | 629-11-8 |
| Molecular Formula | C6H14O2 |
| Molecular Weight | 118.17 |
品类工艺支持
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概况
Hexane-1,6-diol (CAS 629-11-8, MF C6H14O2, MW 118.17) is used as a PROTAC research building block in degrader chemistry. Typical chemistry questions involve route design for the bifunctional architecture, linker selection, and analytical control of residual reagents. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
应用
- Hexane-1,6-diol (CAS 629-11-8) preparation, route refinement, and analytical-control planning
- PROTAC building block — linker / E3-ligand / degrader handle
- Bifunctional degrader synthesis with orthogonal protecting groups
- Linker-length and composition exploration for degrader optimisation