Bis(2-bromoethyl) ether
化学名称
1-bromo-2-(2-bromoethoxy)ethane
Bis(2-bromoethyl) ether•PROTAC
Structure: 
产品编号
CH56002
CAS
5414-19-7
分子式
C4H8Br2O
分子量
231.91
规格标准
| Catalog No. | CH56002 |
| CAS No. | 5414-19-7 |
| Molecular Formula | C4H8Br2O |
| Molecular Weight | 231.91 |
品类工艺支持
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概况
Bis(2-bromoethyl) ether (also known as 1-bromo-2-(2-bromoethoxy)ethane) (CAS 5414-19-7, MF C4H8Br2O, MW 231.91) is a PROTAC research building block — typically a linker, E3-ligase ligand, or degrader handle. Practical chemistry topics include orthogonal protecting groups, modular linker chemistry, and stereo-purity at chiral centres. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
应用
- Bis(2-bromoethyl) ether (CAS 5414-19-7) route review and custom analog preparation
- Reference material in targeted protein degradation chemistry programs
- PROTAC building block — linker / E3-ligand / degrader handle
- Bifunctional degrader synthesis with orthogonal protecting groups