Azido-PEG4-alcohol
化学名称
2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol
Azido-PEG4-alcohol•PROTAC
Structure: 
产品编号
CH56006
CAS
86770-67-4
分子式
C8H17N3O4
分子量
219.24
规格标准
| Catalog No. | CH56006 |
| CAS No. | 86770-67-4 |
| Molecular Formula | C8H17N3O4 |
| Molecular Weight | 219.24 |
品类工艺支持
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概况
Azido-PEG4-alcohol (also known as 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol) (CAS 86770-67-4, MF C8H17N3O4, MW 219.24) is a PROTAC research building block — typically a linker, E3-ligase ligand, or degrader handle. Practical chemistry topics include orthogonal protecting groups, modular linker chemistry, and stereo-purity at chiral centres. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.
应用
- Azido-PEG4-alcohol (CAS 86770-67-4) route review and custom analog preparation
- PROTAC building block — linker / E3-ligand / degrader handle
- Linker-length and composition exploration for degrader optimisation
- Process-development support for scalable building-block preparation