Ethyl hydroxyacetate
化学名称
ethyl 2-hydroxyacetate
Ethyl hydroxyacetate•PROTAC
Structure: 
产品编号
CH56007
CAS
623-50-7
分子式
C4H8O3
分子量
104.1
规格标准
| Catalog No. | CH56007 |
| CAS No. | 623-50-7 |
| Molecular Formula | C4H8O3 |
| Molecular Weight | 104.1 |
品类工艺支持
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概况
Ethyl hydroxyacetate (also known as ethyl 2-hydroxyacetate) (CAS 623-50-7, MF C4H8O3, MW 104.1) is a PROTAC research building block — typically a linker, E3-ligase ligand, or degrader handle. Practical chemistry topics include orthogonal protecting groups, modular linker chemistry, and stereo-purity at chiral centres. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.
应用
- Ethyl hydroxyacetate (623-50-7) supply and analog preparation for research programs
- Linker-length and composition exploration for degrader optimisation
- Custom analog synthesis with controlled coupling handles
- Process-development support for scalable building-block preparation