Methyl 3-hydroxypropanoate
Methyl 3-hydroxypropanoate•PROTAC
Structure: 
产品编号
CH56008
CAS
6149-41-3
分子式
C4H8O3
分子量
104.1
规格标准
| Catalog No. | CH56008 |
| CAS No. | 6149-41-3 |
| Molecular Formula | C4H8O3 |
| Molecular Weight | 104.1 |
品类工艺支持
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概况
Methyl 3-hydroxypropanoate (CAS 6149-41-3, MF C4H8O3, MW 104.1) belongs to the PROTAC building-block class (linker / E3 ligand / warhead). Programs working with this compound typically focus on coupling-handle compatibility, linker length / composition exploration, and impurity control. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.
应用
- Methyl 3-hydroxypropanoate (6149-41-3) as a starting point for downstream chemistry programs
- Reference material in targeted protein degradation chemistry programs
- Bifunctional degrader synthesis with orthogonal protecting groups
- Custom analog synthesis with controlled coupling handles