tert-Butyl (8-aminooctyl)carbamate
化学名称
tert-butyl N-(8-aminooctyl)carbamate
tert-Butyl (8-aminooctyl)carbamate•PROTAC
Structure: 
产品编号
CH56011
CAS
88829-82-7
分子式
C13H28N2O2
分子量
244.37
规格标准
| Catalog No. | CH56011 |
| CAS No. | 88829-82-7 |
| Molecular Formula | C13H28N2O2 |
| Molecular Weight | 244.37 |
品类工艺支持
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概况
tert-Butyl (8-aminooctyl)carbamate (also known as tert-butyl N-(8-aminooctyl)carbamate) (CAS 88829-82-7, MF C13H28N2O2, MW 244.37) is used as a PROTAC research building block in degrader chemistry. Typical chemistry questions involve route design for the bifunctional architecture, linker selection, and analytical control of residual reagents. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.
应用
- tert-Butyl (8-aminooctyl)carbamate (CAS 88829-82-7) route review and custom analog preparation
- Reference material in targeted protein degradation chemistry programs
- PROTAC building block — linker / E3-ligand / degrader handle
- Bifunctional degrader synthesis with orthogonal protecting groups