Fmoc-NH-PEG4-CH2CH2COOH
化学名称
3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Fmoc-NH-PEG4-CH2CH2COOH•PROTAC
Structure: 
产品编号
CH56015
CAS
557756-85-1
分子式
C26H33NO8
分子量
487.54
规格标准
| Catalog No. | CH56015 |
| CAS No. | 557756-85-1 |
| Molecular Formula | C26H33NO8 |
| Molecular Weight | 487.54 |
品类工艺支持
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概况
Fmoc-NH-PEG4-CH2CH2COOH (also known as 3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid) (CAS 557756-85-1, MF C26H33NO8, MW 487.54) belongs to the PROTAC building-block class (linker / E3 ligand / warhead). Programs working with this compound typically focus on coupling-handle compatibility, linker length / composition exploration, and impurity control. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
应用
- Fmoc-NH-PEG4-CH2CH2COOH (557756-85-1) as a starting point for downstream chemistry programs
- Custom analog synthesis with controlled coupling handles
- Process-development support for scalable building-block preparation
- Reference material in targeted protein degradation chemistry programs