Boc-NH-C4-Br

Boc-NH-C4-Br

化学名称

tert-Butyl N-(4-bromobutyl)carbamate

Boc-NH-C4-BrPROTAC
Structure: Boc-NH-C4-Br structure, CAS 164365-88-2, MW 252.15
产品编号
CH56020
CAS
164365-88-2
分子式
C9H18BrNO2
分子量
252.15
规格标准
Catalog No.CH56020
CAS No.164365-88-2
Molecular FormulaC9H18BrNO2
Molecular Weight252.15

品类工艺支持

CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.

概况

Boc-NH-C4-Br (also known as tert-Butyl N-(4-bromobutyl)carbamate) (CAS 164365-88-2, MF C9H18BrNO2, MW 252.15) belongs to the PROTAC building-block class (linker / E3 ligand / warhead). Programs working with this compound typically focus on coupling-handle compatibility, linker length / composition exploration, and impurity control. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.

应用

  • Boc-NH-C4-Br (164365-88-2) supply and analog preparation for research programs
  • PROTAC building block — linker / E3-ligand / degrader handle
  • Linker-length and composition exploration for degrader optimisation
  • Process-development support for scalable building-block preparation

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