Tasisulam
化学名称
N-(5-bromothiophen-2-yl)sulfonyl-2,4-dichlorobenzamide
Tasisulam•Molecular Glues
Structure: 
产品编号
CH57003
CAS
519055-62-0
分子式
C11H6BrCl2NO3S2
分子量
415.11
规格标准
| Catalog No. | CH57003 |
| CAS No. | 519055-62-0 |
| Molecular Formula | C11H6BrCl2NO3S2 |
| Molecular Weight | 415.11 |
品类工艺支持
CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.
概况
Tasisulam (also known as N-(5-bromothiophen-2-yl)sulfonyl-2,4-dichlorobenzamide) (CAS 519055-62-0, MF C11H6BrCl2NO3S2, MW 415.11) is a small-molecule scaffold studied in targeted protein degradation research, with potential relevance to molecular glue or E3-ligase modulation chemistry. Practical chemistry topics include enantioselective synthesis, scaffold modification, and related-substance profiling. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
应用
- Tasisulam (519055-62-0) as a starting point for downstream chemistry programs
- Molecular glue research scaffold for targeted protein degradation
- Custom synthesis of analog series for SAR exploration
- Reference research scaffold in degrader chemistry programs