PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
Indisulam
Indisulam
产品编号CH57004CAS号165668-41-7
产品概述
快速信息
- 产品系列
- PROTAC, E3 Ligands & Proximity-Inducing Building Blocks
- 化学名称
- Indisulam
- 分子式
- C14H12ClN3O4S2
- 分子量
- 385.8
Indisulam is an indole-linked sulfonamide compound identified by CAS 165668-41-7.
The verified record matches molecular formula C14H12ClN3O4S2, molecular weight about 385.8, PubChem CID 216468, and InChIKey SETFNECMODOHTO-UHFFFAOYSA-N.
Published records place Indisulam in RBM39/DCAF15 and molecular-glue research discussions; the identifiers below keep that context attached to the confirmed compound identity.
身份与规格
| Catalog No. | CH57004 |
| CAS No. | 165668-41-7 |
| Chemical Name | Indisulam |
| Molecular Formula | C14H12ClN3O4S2 |
| Molecular Weight | 385.8 |
| PubChem CID | 216468 |
| IUPAC Name | 4-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide |
| InChIKey | SETFNECMODOHTO-UHFFFAOYSA-N |
应用背景
- RBM39/DCAF15 research: Indisulam appears in published literature discussing RBM39/DCAF15-associated molecular-glue research.
- Indole sulfonamide identity reference: supports comparison of the chloroindole and benzenedisulfonamide structural features.
- Catalog data alignment: helps keep CAS 165668-41-7, formula C14H12ClN3O4S2, PubChem CID 216468, and InChIKey SETFNECMODOHTO-UHFFFAOYSA-N consistent across records.
补充物料信息
特性
- Indole-linked disulfonamide structure containing a chloroindole group.
- Sulfur-containing heteroaromatic compound with formula C14H12ClN3O4S2.
- CAS and exact-name lookups both resolve to PubChem CID 216468.
相关技术资源
公开来源
- Indisulam | PubChem CID 216468
- Catalytic in vivo protein knockdown by small-molecule PROTACs
Nature Chemical Biology, 2015
Product-family technical context
- Structural basis of PROTAC cooperative recognition for selective protein degradation
Nature Chemical Biology, 2017
Product-family technical context
- Structural Basis of PROTAC Cooperative Recognition for Selective Protein Degradation
Nature Chemical Biology, 2017
Product-family technical context
- Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
ACS Medicinal Chemistry Letters, 2022
Product-family technical context
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