NRX-103094
化学名称
3-[[4-(2,6-dichlorophenyl)sulfanyl-2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carbonyl]amino]benzoic acid
NRX-103094•Molecular Glues
Structure: 
产品编号
CH57008
CAS
2763260-36-0
分子式
C20H11Cl2F3N2O4S
分子量
503.28
规格标准
| Catalog No. | CH57008 |
| CAS No. | 2763260-36-0 |
| Molecular Formula | C20H11Cl2F3N2O4S |
| Molecular Weight | 503.28 |
品类工艺支持
CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.
概况
NRX-103094 (also known as 3-[[4-(2,6-dichlorophenyl)sulfanyl-2-oxo-6-(trifluoromethyl)-1H-pyridine-3-carbonyl]amino]benzoic acid) (CAS 2763260-36-0, MF C20H11Cl2F3N2O4S, MW 503.28) is a small-molecule scaffold studied in targeted protein degradation research, with potential relevance to molecular glue or E3-ligase modulation chemistry. Practical chemistry topics include enantioselective synthesis, scaffold modification, and related-substance profiling. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.
应用
- NRX-103094 (2763260-36-0) supply and analog preparation for research programs
- Custom synthesis of analog series for SAR exploration
- Process-development support for scalable scaffold preparation
- Reference research scaffold in degrader chemistry programs