dCeMM1

dCeMM1

化学名称

N-[(E)-(5-bromo-2-hydroxyphenyl)methylideneamino]-4-methylbenzenesulfonamide

dCeMM1Molecular Glues
Structure: dCeMM1 structure, CAS 118719-16-7, MW 369.23362
产品编号
CH57009
CAS
118719-16-7
分子式
C14H13BrN2O3S
分子量
369.23362
规格标准
Catalog No.CH57009
CAS No.118719-16-7
Molecular FormulaC14H13BrN2O3S
Molecular Weight369.23362

品类工艺支持

CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.

概况

dCeMM1 (also known as N-[(E)-(5-bromo-2-hydroxyphenyl)methylideneamino]-4-methylbenzenesulfonamide) (CAS 118719-16-7, MF C14H13BrN2O3S, MW 369.23362) is studied as a molecular glue / E3-ligase research scaffold for targeted protein degradation. Practical chemistry questions involve route consistency, chiral integrity, and analytical control of related impurities. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.

应用

  • dCeMM1 (CAS 118719-16-7) preparation, route refinement, and analytical-control planning
  • Analog screening for E3-ligase recruitment chemistry
  • Custom synthesis of analog series for SAR exploration
  • Process-development support for scalable scaffold preparation

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