2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one
2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one•Molecular Glues
Structure: 
产品编号
CH57016
CAS
1333248-18-2
分子量
406.48
规格标准
| Catalog No. | CH57016 |
| CAS No. | 1333248-18-2 |
| Molecular Weight | 406.48 |
品类工艺支持
CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.
概况
2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one (CAS 1333248-18-2, MW 406.48) is part of the small-molecule research-tool class for targeted protein degradation programs (molecular glue or related modality). Programs working with this compound typically examine stereo-purity, analog series, and the behaviour of the warhead under storage. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.
应用
- 2-((4-Acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one (CAS 1333248-18-2) preparation, route refinement, and analytical-control planning
- Analog screening for E3-ligase recruitment chemistry
- Process-development support for scalable scaffold preparation
- Molecular glue research scaffold for targeted protein degradation