XMU-MP-8
化学名称
1-[3-[1-methyl-4-(pyridin-3-ylmethylamino)pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-3-[3-(trifluoromethyl)phenyl]thiourea
XMU-MP-8•Molecular Glues
Structure: 
产品编号
CH57018
CAS
2271314-01-1
分子式
C26H21F3N8S
分子量
534.56
规格标准
| Catalog No. | CH57018 |
| CAS No. | 2271314-01-1 |
| Molecular Formula | C26H21F3N8S |
| Molecular Weight | 534.56 |
品类工艺支持
CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.
概况
XMU-MP-8 (also known as 1-[3-[1-methyl-4-(pyridin-3-ylmethylamino)pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-3-[3-(trifluoromethyl)phenyl]thiourea) (CAS 2271314-01-1, MF C26H21F3N8S, MW 534.56) is a small-molecule scaffold studied in targeted protein degradation research, with potential relevance to molecular glue or E3-ligase modulation chemistry. Practical chemistry topics include enantioselective synthesis, scaffold modification, and related-substance profiling. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.
应用
- XMU-MP-8 (2271314-01-1) supply and analog preparation for research programs
- Process-development support for scalable scaffold preparation
- Reference research scaffold in degrader chemistry programs
- Molecular glue research scaffold for targeted protein degradation