(S,R,S)-AHPC
化学名
(2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
(S,R,S)-AHPC•PROTAC
Structure: 
製品番号
CH56013
CAS
1448297-52-6
分子式
C22H30N4O3S
分子量
430.56
仕様
| Catalog No. | CH56013 |
| CAS No. | 1448297-52-6 |
| Molecular Formula | C22H30N4O3S |
| Molecular Weight | 430.56 |
CHEMOS Support for This Category
CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.
概要
(S,R,S)-AHPC (also known as (2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide) (CAS 1448297-52-6, MF C22H30N4O3S, MW 430.56) belongs to the PROTAC building-block class (linker / E3 ligand / warhead). Programs working with this compound typically focus on coupling-handle compatibility, linker length / composition exploration, and impurity control. CHEMOS process chemistry, organic synthesis routes and project scale-up support are offered for downstream programs.
アプリケーション
- (S,R,S)-AHPC (1448297-52-6) supply and analog preparation for research programs
- Process-development support for scalable building-block preparation
- Reference material in targeted protein degradation chemistry programs
- PROTAC building block — linker / E3-ligand / degrader handle