CHEMOS
Oligonucleotide Synthesis, RNA Raw Materials & Modification

2'-Deoxyuridine

1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

製品番号CH64005CAS番号951-78-0純度>99.0% (HPLC)
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製品概要

クイックビュー

製品ファミリー
Oligonucleotide Synthesis, RNA Raw Materials & Modification
化学名
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
分子式
C9H12N2O5
分子量
228.20
純度
>99.0% (HPLC)

2'-Deoxyuridine (dU) is the uracil DNA nucleoside formed from uracil and 2-deoxy-β-D-ribose. CH64005 is listed under CAS 951-78-0, molecular formula C9H12N2O5, molecular weight 228.20, and PubChem CID 13712.

This record is distinct from uridine, the corresponding RNA nucleoside. In research literature, 2'-deoxyuridine appears as a substrate in thymidylate synthase activity assays and as a reference nucleoside for uracil-in-DNA and base-excision-repair studies.

別名

2'-Deoxyuridine; deoxyuridine; dUrd; dU; 2'-deoxyribouridine

同定情報と仕様

Catalog No.CH64005
CAS No.951-78-0
Molecular FormulaC9H12N2O5
Molecular Weight228.20
PubChem CID13712
InChIKeyMXHRCPNRJAMMIM-SHYZEUOFSA-N
Purity>99.0% (HPLC)

保管条件

Room temperature; cool and dark place below 15 C; inert gas

技術属性

Nucleobase
Uracil
Sugar
2'-Deoxyribose
Nucleoside class
Pyrimidine 2'-deoxyribonucleoside
Packaging
1 g glass bottle with plastic insert; Custom packaging on request
Physical form
Solid; white to almost white powder to crystal

用途情報

  • Thymidylate synthase assay research: [5-³H]-2'-deoxyuridine is reported as the substrate in in situ thymidylate synthase activity assays.
  • Base-excision-repair studies: uracil arising from dU in DNA is removed by uracil-DNA glycosylase, placing deoxyuridine in uracil-in-DNA research contexts.
  • dU nucleoside reference: CH64005 provides the dU identity for nucleoside and oligonucleotide chemistry comparisons.

関連技術資料

オリゴヌクレオチド修飾

ASO、siRNA、guide RNA、aptamer、研究用オリゴの糖、塩基、骨格、末端、コンジュゲーション修飾。

オリゴヌクレオチド合成

修飾モノマー、担体、硫化試薬、キャップ 類似体、関連するオリゴ合成入力物の支援。

公開情報源

よくある質問

Is CH64005 the DNA or RNA nucleoside?

It is 2'-deoxyuridine (dU), the deoxyribonucleoside of uracil. The RNA counterpart, uridine, is listed separately by CHEMOS.

Why is 2'-deoxyuridine used in DNA-repair research?

Uracil that ends up in DNA (via dU/dUMP) is recognized and removed by uracil-DNA glycosylase, so 2'-deoxyuridine is a reference nucleoside in base-excision-repair studies.

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