Cytidine
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
製品概要
クイックビュー
- 製品ファミリー
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 化学名
- 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- 分子式
- C9H13N3O5
- 分子量
- 243.22
- 純度
- >98.0% (HPLC, titration)
Cytidine is the canonical pyrimidine RNA nucleoside, with cytosine linked to β-D-ribose. CH64010 is identified by CAS 65-46-3, molecular formula C9H13N3O5, molecular weight 243.22, and PubChem CID 6175. It is the ribose counterpart of 2'-deoxycytidine, which is cataloged separately as CH64002.
The supported research context is pyrimidine salvage and RNA nucleoside chemistry: cytidine is a uridine-cytidine kinase substrate and an unmodified pyrimidine ribonucleoside reference.
別名
Cytidine; cytosine riboside; Cyd
同定情報と仕様
| Catalog No. | CH64010 |
| CAS No. | 65-46-3 |
| Molecular Formula | C9H13N3O5 |
| Molecular Weight | 243.22 |
| PubChem CID | 6175 |
| InChIKey | UHDGCWIWMRVCDJ-XVFCMESISA-N |
| Purity | >98.0% (HPLC, titration) |
保管条件
Room temperature; cool and dark place below 15 C; inert gas
技術属性
- Nucleobase
- Cytosine
- Sugar
- D-Ribose
- Nucleoside class
- Pyrimidine ribonucleoside
- Packaging
- 1 g glass bottle with plastic insert; Custom packaging on request
- Physical form
- Solid; white to almost white powder to crystal
- Stability
- >=4 years
用途情報
- Uridine-cytidine kinase substrate: cytidine is phosphorylated by UCK in pyrimidine-nucleotide salvage research.
- Pyrimidine RNA nucleoside reference: CH64010 provides the unmodified cytidine identity for RNA and nucleoside chemistry comparisons.
関連技術資料
公開情報源
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem化合物 6175
PubChem · CID 6175
よくある質問
Is CH64010 the RNA or DNA nucleoside?
It is cytidine, the RNA (ribo) nucleoside. The DNA counterpart, 2'-deoxycytidine, is listed separately by CHEMOS.
Why is cytidine used in salvage-pathway research?
Cytidine is a substrate of uridine-cytidine kinase, the rate-limiting enzyme of pyrimidine-nucleotide salvage, so it serves as a reference substrate in salvage studies.
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