CHEMOS
Oligonucleotide Synthesis, RNA Raw Materials & Modification

2'-O-(2-Methoxyethyl)guanosine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

製品番号CH64031CAS番号473278-54-5純度>=98%
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製品概要

クイックビュー

製品ファミリー
Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式
C13H19N5O6
分子量
341.32
純度
>=98%

2'-O-(2-Methoxyethyl)guanosine (2'-O-MOE-G) is guanosine with a 2'-O-(2-methoxyethyl) group on the ribose. CH64031 is identified by CAS 473278-54-5, molecular formula C13H19N5O6, molecular weight 341.32, and PubChem CID 135544588.

In the cited structure and stability literature, 2'-O-MOE ribonucleosides are discussed in RNA-affinity and nuclease-resistance studies and as flanking residues in gapmer antisense oligonucleotides. CH64031 provides the guanosine 2'-O-MOE nucleoside identity for related antisense-oligonucleotide research.

別名

2'-O-(2-Methoxyethyl)guanosine; 2'-O-MOE-G; 2'-MOE-G

同定情報と仕様

Catalog No.CH64031
CAS No.473278-54-5
Molecular FormulaC13H19N5O6
Molecular Weight341.32
PubChem CID135544588
InChIKeyDLLBJSLIKOKFHE-WOUKDFQISA-N
Purity>=98%

保管条件

-20 C

技術属性

Nucleobase
Guanine
Sugar
D-Ribose
Sugar modification
2'-O-(2-Methoxyethyl) (MOE)
Nucleoside class
MOE-modified purine ribonucleoside
Packaging
Custom packaging on request
Physical form
Solid
Stability
>=4 years

用途情報

  • MOE gapmer antisense research: CH64031 is relevant to gapmer antisense studies involving 2'-O-MOE guanine residues.
  • Modified-nucleic-acid studies: cited literature discusses 2'-O-MOE residues in RNA-affinity and nuclease-resistance studies of modified oligonucleotides.
  • 2'-O-MOE nucleoside reference: CH64031 provides the 2'-O-(2-methoxyethyl)guanosine identity for nucleoside chemistry research.

関連技術資料

オリゴヌクレオチド修飾

ASO、siRNA、guide RNA、aptamer、研究用オリゴの糖、塩基、骨格、末端、コンジュゲーション修飾。

オリゴヌクレオチド合成

修飾モノマー、担体、硫化試薬、キャップ 類似体、関連するオリゴ合成入力物の支援。

公開情報源

よくある質問

How is 2'-O-MOE-guanosine different from 2'-O-methylguanosine?

Both are 2'-O-alkyl modifications, but MOE is a larger 2-methoxyethyl group versus a single methyl in 2'-O-methyl. 2'-O-methylguanosine is cataloged separately.

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