CHEMOS
Oligonucleotide Synthesis, RNA Raw Materials & Modification

2'-O-(2-Methoxyethyl)cytidine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

製品番号CH64033CAS番号223777-16-0純度>98.0% (HPLC, titration)
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製品概要

クイックビュー

製品ファミリー
Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式
C12H19N3O6
分子量
301.30
純度
>98.0% (HPLC, titration)

2'-O-(2-Methoxyethyl)cytidine (2'-O-MOE-C) is cytidine with a 2'-O-(2-methoxyethyl) group on the ribose. CH64033 is identified by CAS 223777-16-0, molecular formula C12H19N3O6, molecular weight 301.30, and PubChem CID 11077469.

In the cited structure and stability literature, 2'-O-MOE ribonucleosides are discussed in RNA-affinity and nuclease-resistance studies and as flanking residues in gapmer antisense oligonucleotides. CH64033 provides the cytidine 2'-O-MOE nucleoside identity for related antisense-oligonucleotide research.

別名

2'-O-(2-Methoxyethyl)cytidine; 2'-O-MOE-C; 2'-MOE-C

同定情報と仕様

Catalog No.CH64033
CAS No.223777-16-0
Molecular FormulaC12H19N3O6
Molecular Weight301.30
PubChem CID11077469
InChIKeyYKOGMMXZKKVMBT-QCNRFFRDSA-N
Purity>98.0% (HPLC, titration)

保管条件

0-10 C

技術属性

Nucleobase
Cytosine
Sugar
D-Ribose
Sugar modification
2'-O-(2-Methoxyethyl) (MOE)
Nucleoside class
MOE-modified pyrimidine ribonucleoside
Packaging
200 mg; 1 g; Custom packaging on request
Physical form
Solid; white to yellow powder to crystal

用途情報

  • MOE gapmer antisense research: CH64033 is relevant to gapmer antisense studies involving 2'-O-MOE cytidine residues.
  • Modified-nucleic-acid studies: cited literature discusses 2'-O-MOE residues in RNA-affinity and nuclease-resistance studies of modified oligonucleotides.
  • 2'-O-MOE nucleoside reference: CH64033 provides the 2'-O-(2-methoxyethyl)cytidine identity for nucleoside chemistry research.

関連技術資料

オリゴヌクレオチド修飾

ASO、siRNA、guide RNA、aptamer、研究用オリゴの糖、塩基、骨格、末端、コンジュゲーション修飾。

オリゴヌクレオチド合成

修飾モノマー、担体、硫化試薬、キャップ 類似体、関連するオリゴ合成入力物の支援。

公開情報源

よくある質問

How is 2'-O-MOE-cytidine different from 2'-O-methylcytidine?

Both are 2'-O-alkyl modifications, but MOE is a larger 2-methoxyethyl group versus a single methyl in 2'-O-methyl. 2'-O-methylcytidine is cataloged separately.

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