7-Deaza-7-Iodo-2'-deoxyguanosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
製品概要
クイックビュー
- 製品ファミリー
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 分子式
- C11H13IN4O4
- 分子量
- 392.15
- 純度
- >=98%
7-Deaza-7-Iodo-2'-deoxyguanosine is 7-deaza-2'-deoxyguanosine carrying an iodine at the C7 position of the pyrrolo[2,3-d]pyrimidine base. CH64047 is identified by CAS 172163-62-1, molecular formula C11H13IN4O4, molecular weight 392.15, PubChem CID 135405252, and InChIKey TVQBNMOSBBMRCZ-RRKCRQDMSA-N.
In the cited 7-deazapurine literature, the C7-halogen position is discussed as a functionalization point for palladium cross-coupling reactions such as Sonogashira or Suzuki coupling. CH64047 provides the 7-deaza-7-iodo-dG identity for C7-functionalized oligonucleotide research.
別名
7-Deaza-7-iodo-2'-deoxyguanosine; 7-iodo-c7dG
同定情報と仕様
| Catalog No. | CH64047 |
| CAS No. | 172163-62-1 |
| Molecular Formula | C11H13IN4O4 |
| Molecular Weight | 392.15 |
| PubChem CID | 135405252 |
| InChIKey | TVQBNMOSBBMRCZ-RRKCRQDMSA-N |
| Purity | >=98% |
保管条件
-20 C
技術属性
- Nucleobase analog
- 7-Deazaguanine
- Sugar
- 2'-Deoxyribose
- Base modification
- 7-Deaza
- C7 substituent
- Iodo cross-coupling handle
- Packaging
- 250 mg; 500 mg; 1 g; Custom packaging on request
- Physical form
- Solid
- Stability
- >=4 years
用途情報
- C7 cross-coupling research: the C7-iodine on the 7-deazapurine base is relevant to Sonogashira/Suzuki-style functionalization studies for C7-modified oligonucleotides.
- Modified-DNA studies: CH64047 combines the N7-removed 7-deazapurine scaffold with a C7 halogen position for base-analog research.
- Base-analog reference: CH64047 provides the 7-deaza-7-iodo-2'-deoxyguanosine identity for nucleoside chemistry research.
関連技術資料
公開情報源
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem化合物 135405252
PubChem · CID 135405252
よくある質問
How is this different from 7-deaza-2'-deoxyguanosine?
It is 7-deaza-2'-deoxyguanosine with an added iodine at C7. The plain 7-deaza-dG is listed separately by CHEMOS.
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