CHEMOS
Oligonucleotide Synthesis, RNA Raw Materials & Modification

5-TFA-ap-2'-deoxycytidine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

製品番号CH64054CAS番号115899-38-2純度97%
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製品概要

クイックビュー

製品ファミリー
Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式
C14H15F3N4O5
分子量
376.29
純度
97%

5-TFA-ap-2'-deoxycytidine is 2'-deoxycytidine that carries a 3-(trifluoroacetamido)prop-1-ynyl amino-linker at the C5 position of cytosine. CH64054 is identified by CAS 115899-38-2, molecular formula C14H15F3N4O5, molecular weight 376.29, PubChem CID 14768553, and InChIKey OKLUSVKQOCPUNW-IVZWLZJFSA-N.

The trifluoroacetyl (TFA) group protects a primary amine on the aminopropynyl linker. The cited labeling literature discusses amine-linker nucleosides as motifs for covalent fluorophore attachment in nucleoside and oligonucleotide labeling research.

別名

5-(3-trifluoroacetamidoprop-1-ynyl)-2'-deoxycytidine; 5-TFA-ap-dC

同定情報と仕様

Catalog No.CH64054
CAS No.115899-38-2
Molecular FormulaC14H15F3N4O5
Molecular Weight376.29
PubChem CID14768553
InChIKeyOKLUSVKQOCPUNW-IVZWLZJFSA-N
Purity97%

保管条件

2-8 C, protect from light

技術属性

Nucleobase
Cytosine
Sugar
2'-Deoxyribose
C5 linker
3-Aminoprop-1-ynyl
Amine protection
Trifluoroacetyl (TFA)
Packaging
100 mg; 250 mg; 1 g; 5 g; 25 uL sample solution; Custom packaging on request
Solution concentration
10 mM supplied sample solution
Physical form
A solid

用途情報

  • Internal-labeling research: CH64054 combines a 2'-deoxycytidine identity with a C5 aminopropynyl linker for oligonucleotide labeling studies.
  • Amine-linker labeling studies: the TFA-protected aminopropynyl group represents a protected amine-linker motif discussed for covalent fluorophore attachment after deprotection.
  • Base-analog reference: CH64054 provides the 5-TFA-ap-2'-deoxycytidine identity for nucleoside chemistry research.

関連技術資料

オリゴヌクレオチド修飾

ASO、siRNA、guide RNA、aptamer、研究用オリゴの糖、塩基、骨格、末端、コンジュゲーション修飾。

オリゴヌクレオチド合成

修飾モノマー、担体、硫化試薬、キャップ 類似体、関連するオリゴ合成入力物の支援。

公開情報源

よくある質問

What do 'TFA' and 'ap' mean in the name?

'ap' is the aminopropynyl (3-aminoprop-1-ynyl) linker at the C5 position of cytosine, and 'TFA' is the trifluoroacetyl group protecting that linker's primary amine.

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