Oligonucleotide Synthesis, RNA Raw Materials & Modification

5-Iodo-2'-deoxycytidine

Oligonucleotide Synthesis, RNA Raw Materials & Modification

製品番号CH64061CAS番号611-53-0純度99.8% (HPLC)

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製品概要

クイックビュー

製品ファミリー: Oligonucleotide Synthesis, RNA Raw Materials & Modification
分子式: C9H12IN3O4
分子量: 353.11
純度: 99.8% (HPLC)

5-Iodo-2'-deoxycytidine is 2'-deoxycytidine bearing an iodine at the C5 position of cytosine. CH64061 is identified by CAS 611-53-0, molecular formula C9H12IN3O4, molecular weight 353.11, PubChem CID 65050, and InChIKey WEVJJMPVVFNAHZ-RRKCRQDMSA-N.

The C5 iodine is a heavy atom on the pyrimidine base. CH64061 provides the 5-iodocytosine deoxynucleoside identity for halogenated-pyrimidine, modified-DNA, and nucleoside chemistry research.

別名

5-Iodo-2'-deoxycytidine; 5-iodo-dC

同定情報と仕様

Catalog No.	CH64061
CAS No.	611-53-0
Molecular Formula	C9H12IN3O4
Molecular Weight	353.11
PubChem CID	65050
InChIKey	WEVJJMPVVFNAHZ-RRKCRQDMSA-N
Purity	99.8% (HPLC)

保管条件

-20 C

技術属性

Nucleobase: Cytosine
Sugar: 2'-Deoxyribose
Base substituent: 5-Iodo
Nucleoside class: Halogenated pyrimidine deoxyribonucleoside
Grade: N (Normal)
Packaging: 1 g; Custom packaging on request
Physical form: solid; white to almost white powder to crystal
Stability: >=4 years

用途情報

Halogenated pyrimidine research: the C5 iodine on cytosine supports heavy-atom base-analog work in modified-DNA and nucleoside chemistry research.
Base-analog reference: CH64061 provides the 5-iodo-2'-deoxycytidine identity for nucleoside chemistry research.

公開情報源

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
PubChem化合物 65050
PubChem · CID 65050

よくある質問

How does 5-iodo-2'-deoxycytidine differ from 2'-deoxycytidine?

It carries an iodine at the C5 position of cytosine (a heavy atom), whereas 2'-deoxycytidine is unsubstituted. 2'-deoxycytidine is cataloged separately.

How is it related to 5-iodo-2'-deoxyuridine?

Both are C5-iodinated (heavy-atom) pyrimidine deoxynucleosides; this one has a cytosine base, while 5-iodo-2'-deoxyuridine has a uracil base. Both are cataloged separately.