8-Chloroadenosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
製品概要
クイックビュー
- 製品ファミリー
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 分子式
- C10H12ClN5O4
- 分子量
- 301.69
- 純度
- >98% (HPLC)
8-Chloroadenosine is adenosine bearing a chlorine at the C8 position of adenine. CH64068 is identified by CAS 34408-14-5, molecular formula C10H12ClN5O4, molecular weight 301.69, PubChem CID 147569, and InChIKey MHDPPLULTMGBSI-UUOKFMHZSA-N.
The cited literature discusses 8-substituted purine nucleosides and nucleotides in relation to syn/anti glycosidic conformation, including 8-chloro derivatives. CH64068 provides the 8-chloroadenosine identity for conformational, base-analog, and C8-functionalization research contexts.
別名
8-Chloroadenosine; 8-Cl-adenosine; 8-Cl-Ado
同定情報と仕様
| Catalog No. | CH64068 |
| CAS No. | 34408-14-5 |
| Molecular Formula | C10H12ClN5O4 |
| Molecular Weight | 301.69 |
| PubChem CID | 147569 |
| InChIKey | MHDPPLULTMGBSI-UUOKFMHZSA-N |
| Purity | >98% (HPLC) |
保管条件
-20 C
技術属性
- Nucleobase
- Adenine
- Sugar
- D-Ribose
- Base substituent
- 8-Chloro
- Conformational context
- 8-Substituted purine; syn-favoring
- Packaging
- 10 umol (~3 mg); 5 x 10 umol; Custom packaging on request
- Physical form
- solid
- Stability
- >=4 years
用途情報
- syn-Conformation research: the cited literature discusses 8-substituted purines, including 8-chloro derivatives, as systems with defined syn/anti glycosidic conformational behavior.
- C8-functionalization studies: the C8 chlorine marks a chemically addressable position on the adenine base for nucleoside research.
- Base-analog reference: CH64068 provides the 8-chloroadenosine identity for nucleoside chemistry research.
関連技術資料
公開情報源
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem化合物 147569
PubChem · CID 147569
よくある質問
How does it differ from adenosine?
It carries a chlorine at the C8 position of adenine, whereas adenosine is unsubstituted. Adenosine is cataloged separately.
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