8-Thioadenosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
製品概要
クイックビュー
- 製品ファミリー
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- 分子式
- C10H13N5O4S
- 分子量
- 299.31
- 純度
- >=97%
8-Thioadenosine (8-mercaptoadenosine) is adenosine bearing a thiol/thioxo group at the C8 position of adenine. CH64070 is identified by CAS 3001-45-4, molecular formula C10H13N5O4S, molecular weight 299.31, PubChem CID 10615718, and InChIKey QILZVYQRHGBEAR-UUOKFMHZSA-N.
The cited literature discusses bulky C8 substitution in purine nucleosides and nucleotides in relation to syn glycosidic conformation. CH64070 provides the 8-thioadenosine identity for base-analog, bulky-C8 purine, and nucleoside chemistry research.
別名
8-Thioadenosine; 8-mercaptoadenosine
同定情報と仕様
| Catalog No. | CH64070 |
| CAS No. | 3001-45-4 |
| Molecular Formula | C10H13N5O4S |
| Molecular Weight | 299.31 |
| PubChem CID | 10615718 |
| InChIKey | QILZVYQRHGBEAR-UUOKFMHZSA-N |
| Purity | >=97% |
保管条件
sealed and dry at 2-8 C
技術属性
- Nucleobase
- Adenine
- Sugar
- D-Ribose
- Base modification
- 8-Thio (8-mercapto)
- Conformational context
- 8-Substituted purine; syn-favoring
- Packaging
- 100 mg; 250 mg; 1 g; 5 g; 10 g; Custom packaging on request
- Stability
- Powder: 3 years; in solution: 1 year
用途情報
- 8-Substituted purine research: CH64070 is a C8-thio adenosine analog for bulky-C8 purine and syn/anti glycosidic conformation research contexts.
- Base-analog reference: CH64070 provides the 8-thioadenosine identity for nucleoside chemistry research.
関連技術資料
公開情報源
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem化合物 10615718
PubChem · CID 10615718
よくある質問
What kind of modification does 8-thioadenosine carry?
It has a thiol/thioxo (mercapto) group at the C8 position of adenine, making it an 8-substituted bulky-C8 purine nucleoside.
How does it differ from adenosine?
It carries a C8-thio group, whereas adenosine is unsubstituted. Adenosine is cataloged separately.
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